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Leukopenia – Decreased number of white blood cells : causes, symptoms and treatment.

Leukopenia is the decreased number of white blood cells in blood. It is a blood disease usually caused by a decrease in the granulocyte numbers, particularly the blood neutrophils. White blood cells protect the body against infections, diseases and foreign particles. The normal white blood cell count is between 5000 to 10000 per cubic milli meter. When the total white cell count drops below 4000 per cubic millimeter in the blood, the person is said to be suffering from leucopenia.


– Some medications like antipsychotic drugs, immunosuppressive drugs, interferons, and some antidepressants.
– Some cancer treatment.
– Diseases such as HIV, and even influenza.
– Mineral deficiencies like copper, zinc.
– Sepsis, and aplastic anemia.
– Enlargement of spleen.
– Radiation.
– Folate deficiencies.


Mild cases do not show much symptoms.
– Anemia.
– Pneumonia.
– Liver abscess.
– Mouth inflammation.
– Headache.
– Fever.
– Craving for hot drinks.
– Irritability.
– Sore throat and skin rash.
– Sores on body, mouth, around the rectum and vagina.
– The person becomes susceptible to various infections and oral ulcers.


A complete blood cell count is usually sufficient to confirm the disease. This blood test is called a complete blood count (CBC) and will measure the amount of white blood cells in the blood. This is typically the only way to tell if someone has an abnormally low amount.

In certain cases treatments such as chemotherapy and cytokine therapy have been used. Chronic Leukopenia can lead to vulnerability to the infections, hence it is advisable to consult the doctor and take necessary precautions.

1 comment to Leukopenia – Decreased number of white blood cells : causes, symptoms and treatment.

  • Damian Hall

    Hello I’m Damian M Hall from Florida. I was diagnosed with leukopenia/thrombocytopenia. I hope someone can give me more info or help me cope with this illness.

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