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What are causes and scope of liver cancer?

The liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions.
– The liver is necessary for survival.
– This organ plays a major role in metabolism.
– It lies below the diaphragm in the abdominal-pelvic region of the abdomen.
– It produces bile, an alkaline compound which aids in digestion.
– It does so via the emulsification of lipids.
– The liver’s highly specialized tissues regulate a wide variety of high-volume biochemical reactions.
– The reactions include the synthesis and breakdown of small and complex molecules that are necessary for normal vital functions.
– Medical terms related to the liver often start in hepato- or hepatic.
– This comes from the Greek word for liver, hēpar.

Functions of Liver
More than 500 vital functions have been identified with the liver. The functions include:
– Detoxification.
– Protein synthesis.
– Production of biochemicals that are necessary for digestion.
– Glycogen storage.
– Decomposition of red blood cells.
– Plasma protein synthesis.
– Hormone production.
– Production of bile for digestion.
– Production of certain proteins for blood plasma.
– Production of cholesterol and special proteins that help to carry fats through the body.
– Conversion of excess glucose into glycogen for storage.
– Regulation of blood levels of amino acids.
– These amino acids form the building blocks of proteins.
– Processing of hemoglobin – the liver stores iron.
– Conversion of poisonous ammonia to urea.
– Clearing the blood of drugs and other poisonous substances.
– Regulating blood clotting.
– Resisting infections by producing immune factors.
– Removing bacteria from the bloodstream.
– Liver breaks down harmful substances which are excreted into the bile or blood.
– Bile by-products enter the intestine and ultimately leave the body in the feces.

Scope and Causes of the Liver Cancer
– Liver cancer is the third most common cancer in the world.
– Liver cancer will kill almost all patients who have it.
– It is known to kill almost within a year.
– About three-quarters of the cases of liver cancer are found in Southeast Asia (China, Hong Kong, Taiwan, Korea, and Japan).
– Liver cancer is also very common in sub-Saharan Africa (Mozambique and South Africa).
– Usually it is due to the prevalence of hepatitis B infection, which is the most common cause of this cancer worldwide.
– The reasons can also be due to rising obesity and diabetes rates.
– People who are prone to chronic hepatitis C which is another infection of the liver, causes liver cancer.
– l-carnitine deficiency is a risk factor for liver cancer
– Japan being member of International Cancer Genome Consortium is leading efforts to map liver cancer’s complete genome.

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