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What is the impact of obesity on diabetes type 2?

• More than 80 percent of people with Type 2 diabetes, the most common form of the disease, are obese or overweight.
• Data from the Centers for Disease Control and Prevention (CDC) National Health and Nutrition Examination Survey III shows that two-thirds of adult men and women are diagnosed with Type 2 diabetes have a body mass index (BMI)of 27 or greater.
• This BMI is classified as overweight and unhealthy.
• Type 2 diabetes develops when either the body does not produce enough insulin in the blood or cells ignore the insulin produced.
• As obesity diminishes insulin’s ability to control blood sugar, there is an increased risk of developing diabetes because the body begins overproducing insulin to regulate blood sugar levels.
• Over time, the body is no longer able to keep blood sugar levels in the normal range.

The inability to achieve healthy blood sugar balance results in the development of Type 2 diabetes.
• Obesity complicates the management and treatment of Type 2 diabetes by increasing insulin resistance and glucose intolerance.
• This makes drug treatment for the disease less effective.

Normal Impression of People

• This is a real and simple example of an externality.
• A fat person is fat because they eat too much.
• The major cause of that is carbs, not fats or proteins.
• The fat person chooses to do this act like an alcoholic, cigarette smoker, drug addict, person afflicted with a sexually transmitted disease, these are all diseases of choice.

About Studies

• Type 2 diabetes is characterized by both fasting and postprandial hyperglycemia.
• Numerous studies have established that glucose production in people with type 2 diabetes is either elevated or not appropriate for the prevailing glucose and insulin concentrations.
• The cause(s) of these inappropriately elevated rates of glucose production remains an area of active investigation.
• A series of studies have shown that gluconeogenesis, whether measured with magnetic resonance spectroscopy or the deuterated water method, is increased in people with type 2 diabetes.
• On the other hand, rates of glycogenolysis have been reported to not differ in diabetic and non-diabetic individuals.
• Both hyperglycemia and hyperinsulinemia are potent inhibitors of glycogenolysis, equal rates of glycogenolysis, despite higher glucose and insulin concentrations in diabetic subjects, imply abnormal regulation of the glycogenolytic as well as the gluconeogenic pathway.
• The contribution of gluconeogenesis to endogenous glucose production was elevated in the subjects with severe diabetes during the clamp when glucagon as well as glucose and insulin concentrations were matched.
• It was reported that obesity as well as type 2 diabetes impairs insulin-induced suppression of glycogenolysis as well as gluconeogenesis and that the degree of impairment correlates with plasma free fatty acid (FFA) concentrations.

Diabesity The Blood Sugar Solution Defeating Obesity, Diabetes and High Blood Pressure

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