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Explain Birth Defects – Part 1

• A congenital anomaly also known as a genetic disorder is actually a condition existing at birth and infrequently before birth.
• It can be a condition that develops during the first month of life, regardless of causation.
• Of these diseases, those characterized by structural deformities are termed “congenital anomalies”.
• It involves defects or problems for a developing fetus.

A congenital abnormality will be the result of:
– Genetic abnormalities
– The intrauterine environment
– Errors of morphogenesis
– Infection
– A chromosomal abnormality
• The actual end result on the disorder would depend on complex interactions that relate to the pre-natal deficit and the post-natal environment.

Usually the reports indicate the factors that are responsible for long-term effects on fetal growth and adolescent and adult disease as:
– mother’s diet
– vitamin intake
– glucose levels just before ovulation
– conception
• Congenital disorders vary widely in causation and abnormalities.
• Any substance that creates birth defects is known as a teratogen.
• The term “congenital “disorder may not refer to an innate disorder.
• Some disorders could be detected before birth through prenatal diagnosis.

Classification of Birth Defects

• A lot of the language used for describing congenital conditions predates genomic mapping.
• Structural conditions are often considered variant from other congenital conditions.
• It is now known that a large number of metabolic conditions could have subtle structural expression and structural conditions with genetic links.
• Congenital is often classified on a structural basis.
• It is possible when primary organ system is affected.
• Several terms are employed describe congenital abnormalities.
• A congenital physical anomaly is definitely an abnormality from the structure of the body part.
• An anomaly may or may not be perceived as problem condition.
• Several people have a number of minor physical anomalies when examined carefully.

Instances of minor anomalies can incorporate:
– curvature with the 5th finger
– another nipple
– tiny indentations on the epidermis near the ears
– shortness in the 4th metacarpal or metatarsal bones
– dimples within the lower spine.
• Some minor anomalies could be clues to more significant internal abnormalities.
• Congenital anomaly is a trusted term for the congenital malformation.
• A congenital can be a physical anomaly which is recognizable at birth and which is significant enough to be considered as a problem.
• Based on the CDC, most birth defects are considered to be caused by a complex mixture of factors.

These include:
– Genetics
– Environment
– Behaviors
– Many birth defects have zero known cause
• One particular congenital anomaly is cleft palate.
• A congenital malformation is usually a congenital physical anomaly.
• This can be deleterious which means there is a structural defect causing the problem.
• A standard combination of malformations affecting a couple of body parts is called a malformation syndrome.

Some of them are a result of abnormal tissue development:
• A malformation is assigned to a disorder of tissue development.
Malformations often happen in the 1st trimester.
• A dysplasia can be a disorder in the organ level which is due to complications in tissue development.
• It is usually in conditions which arise after the formation of tissue.
• A deformation is a condition arising from mechanical stress on normal tissue.

The Encyclopedia of Genetic Disorders and Birth Defects Birth Defects (Diseases and People) How to Raise a Healthy Child in Spite of Your Doctor

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