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What are different methods to treat leukemia ?

Leukemia is not a single disease. Instead, the term leukemia refers to a number of related cancers that start in the blood-forming cells of the bone marrow. There are both acute and chronic forms of leukemia, each with many subtypes that vary in their response to treatment. Leukemia treatment plans often are personalized and geared toward each individual patient.
In general, there are five major approaches to the treatment of leukemia :

- Chemotherapy is the use of drugs that either kill cancer cells or preventing the cells from dividing. Chemotherapy can be given in a variety of ways, with IV infusion and pill being more common. The type of chemotherapy given depends on the stage and type of lung cancer.
- Interferon therapy to slow the reproduction of leukemia cells and promote the immune system’s anti-leukemia activity. – Radiation therapy to kill cancer cells by exposure to high-energy radiation. It is the use of certain types of energy, radiation is used to kill cancer cells and shrink tumors. This energy can be waves or particles like protons, electrons, x-rays and gamma rays.
- Stem cell transplantation (SCT) to enable treatment with high doses of chemotherapy and radiation therapy.
- Surgery to remove an enlarged spleen or to install a venous access device (large plastic tube) to give medications and withdraw blood samples. The spleen collects leukemia cells and they accumulate, allowing the spleen to enlarge. An enlarged spleen can cause many complications.

Oncologists administer these treatments in a variety of combinations. Each method has its advantages and drawbacks. The treatment of leukemia depends on a number of factors. The most important of these are the histopathologic (diseased tissue) type of leukemia, its stage, and certain prognostic features, such as the patient’s age and overall health.

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Melanoma – Type of skin cancer

Melanoma is a disease of the skin in which cancer cells are found in the melanocytes, the cells that produce color in the skin or pigment known as melanin. Melanoma usually occurs in adults, but it may occasionally be found in children and adolescents. Melanoma may also be called cutaneous melanoma or malignant melanoma. Melanoma is the rarest, but most virulent, form of skin cancer.

- A flat or raised growth of black or brown color, often mixed with blue, red, or white parts, from 6 mm to few cm in size, may appear anywhere on the skin, in men mostly on the trunk, in women on the back and legs, and parts of the skin that are usually hidden from the sun, but were exposed to intense sunlight for short periods.
- Melanoma may show one or more of typical ABCDE characteristics: Asymmetry: one part of the tumor differs from other parts; Border of the tumor is irregular; Color: tumor may be of different colors, often several colors are present in one tumor; Diameter above 6 mm (in most cases), Evolving: lesion growths and changes color and appearance with time.

Melanoma Subtypes :
- Superficially spreading melanoma grows relatively slowly.
- Nodular melanoma grows rapidly – weeks to months. It tends to ulcerate and bleed.
- Acral lentiginous melanoma appears in dark skinned people (Afro-American, Asian, and Hispanic), mostly on their palms, soles, and under nails.
- Lentigo maligna melanoma. A macule grows slowly (years) as a patch, over 1-3 cm in size. It does not spread to other organs.

Treatment :
- Chemotherapy is often used to treat melanoma that has returned or spread.
- Medications such as interferon or interleukin, which boost the immune system to fight the cancer, may be useful in addition to chemotherapy and surgery. This kind of treatment is called immunotherapy. However, interferon has many side effects and can be difficult to tolerate.
- Radiation treatments may be used to relieve pain or discomfort caused by cancer that has spread.
- Cancer that has spread elsewhere in the body is sometimes removed with surgery to relieve pain or discomfort.

Basal Cell Carcinoma – Type of skin cancer

There are a number of different types of skin cancers depending on the type of skin cell from which they arise. Each kind of skin cancer has its own distinctive appearance. Certain skin cancers also tend to develop in specific areas of the body.

BASAL CELL CARCINOMA : This cancer is the most common type, and is the type of skin cancer that 90% of US citizen are diagnosed with.
- Basal cell carcinoma arises from the basal cells in the bottom layer of the epiderrmis – stratum basale.
- Basal cell carcinoma does not metastasize like the other skin cancers, but can still badly damage the area they occupy.
- It resembles a small nodule that is red in color, and located on the face, hands, or sometimes the torso. Occasionally, these nodules appear on the trunk of the body, usually as flat growths.
- Basal cell carcinoma can lead to the loss of organ function on such external organs as the ears or eyes.
- Although most cases of basal cell carcinoma are caused by the sun, other exposures can have the same results. Arsenic, severe burns, tattooing, vaccinations, and radiation can all cause basal cell carcinoma.

The variety in which basal cell carcinoma can appear makes for hard diagnosis. It can hide itself in the form of a mosquito bite, wart, rash, or cyst. For these reasons it is important for one to see a physician if any area of sun exposed skin looks unusual or has had prolonged pain.