Archive for the ‘Malignancy’ category

Treatment options available for treating Uterine Fibroids

May 15th, 2010

Uterine fibroids are the most common pelvic tumors in women, occurring in approximately 30% of women over the age of 35. Although fibroids are benign (non-cancerous), they may produce a wide variety of symptoms including excessive bleeding leading to iron deficiency anemia, pain and pressure sensations, and even obstruction of the bowel or urinary tract.
While it is often easier to treat smaller fibroids than larger ones, many of the small fibroids never will need to be treated.

Treatment with medicines

Abnormal vaginal bleeding caused by fibroids may require scraping of the uterine cavity in a procedure known as a D&C. If no malignancy (cancer) is found, this bleeding often can be controlled by hormonal medications. You may be given nonsteroidal anti-inflammatory drugs, oral contraceptives (birth control pills), gonadotropin releasing hormone agonists, or RU-486.

Surgery

Surgery options for treatment have both risks and benefits.
- Myomectomy is the surgical removal of the fibroids only. This can be accomplished through hysteroscopy, laparoscopy, or, less frequently, an open procedure (an incision in your abdomen). The surgical approach depends on the size and location of your fibroid.
- Hysterectomy is the surgical removal of the uterus (and fibroids). It is the most commonly performed surgical procedure in the treatment of fibroids and is considered a cure. Depending on the size of the fibroid, hysterectomy can be performed through your vagina or abdomen.
- Uterine artery embolization, or clotting of the arterial blood supply to the fibroid, is an innovative approach that has shown promising results. This procedure is done by inserting a catheter (small tube) into an artery of the leg (the femoral artery), using special x-ray video to trace the arterial blood supply to the uterus, then clotting the artery with tiny plastic or gelatin sponge particles the size of grains of sand.
- In a laparotomy, an incision is made in the abdomen to reach the uterus. The advantage of this is that large fibroids can be quickly removed. The surgeon is able to feel the uterus, which is helpful in locating myomas that may be deep in the uterine wall. The disadvantage of a laparotomy is that it requires an abdominal incision.

Types of Thyroid cancer and its symptoms

May 1st, 2010

Thyroid cancer is a cancerous growth of the thyroid gland. The thyroid is a butterfly-shaped gland located at the base of the neck. It produces hormones that regulate the heart rate, blood pressure, body temperature and weight. There are several types of thyroid cancer :

- Papillary thyroid cancer : The papillary type of thyroid cancer is the most common, making up about 80 percent of all thyroid cancer diagnoses. Papillary thyroid cancer can occur at any age, but is most commonly diagnosed in people ages 30 to 50.
- Follicular thyroid cancer : Follicular thyroid cancer also includes Hurthle cell cancer. Follicular thyroid cancer typically occurs in people older than 50. (An estimated 11% of all thyroid cancer cases).
- Medullary thyroid cancer accounts for 5 to 10 percent of thyroid cancer cases. It arises in C cells, not follicular cells. Medullary thyroid cancer is easier to control if it is found and treated before it spreads to other parts of the body.
- Anaplastic thyroid cancer is the least common type of thyroid cancer (only 1 to 2 percent of cases). It arises in the follicular cells. The cancer cells are highly abnormal and difficult to recognize. This type of cancer is usually very hard to control because the cancer cells tend to grow and spread very quickly.
- Thyroid lymphoma : Thyroid lymphoma begins in the immune system cells in the thyroid. Thyroid lymphoma is very rare. It occurs most often in adults age 70 or older.

These rarer types of thyroid cancer are usually more aggressive, with a higher chance of spreading to another part of the body (metastasis).

Symptoms of Thyroid Cancer

- Cough
- Difficulty swallowing
- Enlargement of the thyroid gland
- Hoarseness or changing voice
- Neck swelling
- Thyroid lump (nodule)

How is thyroid cancer diagnosed?

April 29th, 2010

If a person has symptoms that suggest thyroid cancer, the doctor may perform a physical exam and ask about the patient’s personal and family medical history. The doctor also may order laboratory tests and imaging tests to produce pictures of the thyroid and other areas.

The exams and tests may include the following:
- Larger and more anteriorly (front) located nodules can be felt by the examiner.
- A physician will ask about any other medical history and any risk factors for thyroid nodules or cancer, including family history of thyroid cancer or radiation exposure of the head or neck.
- Thyroid stimulating hormone (TSH) levels and levels of thyroid hormone can indicate whether the thyroid is under- or overproducing thyroid hormones.
- Anti-thyroid antibody levels can indicate the presence of autoimmune thyroid inflammation that can be seen with Hashimoto’s thyroiditis.
- Calcitonin levels in the blood can indicate a specific type of thyroid cancer, known as medullary carcinoma of the thyroid.
- Ultrasound : This is a test that uses sound waves to take a picture of the thyroid. An ultrasound can reveal which thyroid nodules are larger than 1-1.5 centimeters, requiring further evaluation for cancer. It includes number of nodules, location of nodules, distinctness of borders, fluid versus solid contents, other nodule contents, such as calcium deposits, or the amount of blood flow.
- Radionuclide scanning : The doctor may order a nuclear medicine scan that uses a very small amount of radioactive material to make thyroid nodules show up on a picture.
- Biopsy : The removal of tissue to look for cancer cells is called a biopsy. A biopsy can show cancer, tissue changes that may lead to cancer, and other conditions. A biopsy is the only sure way to know whether a nodule is cancerous.

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