Secondary Tumor

What is the difference between primary tumors and secondary tumors?

A tumor or tumour is commonly used as a synonym for a neoplasm a solid or fluid-filled(cystic)lesion.
- This may or may not be formed by an abnormal growth of neoplastic cells.
- This appears enlarged in size.
- Tumor is not synonymous with cancer.
- A tumor can be benign, pre-malignant, or malignant.
- It may represent a lesion with no cancerous potential whatsoever.
- The nature of a tumor is determined by imaging, by surgical exploration, by a pathologist after examination of the tissue from a biopsyor a surgical specimen.

Causes
A neoplasm can be caused by:
- an abnormal proliferation of tissues.
- genetic mutations.
- encapsulated glandular swellings (thyroid, adrenal gland, and pancreas).
- encapsulated hematomas.
- encapsulated necrotic tissue (from an insect bite, foreign body, or other noxious mechanism).
- keloids.
- granulomas (discrete overgrowths of scar tissue).

Enlargements of normal structures like:
- ureters,
- blood vessels,
- intrahepatic
- extrahepatic biliary ducts
- pulmonary inclusions
- gastrointestinal duplications

Tumours can be primary and secondary.

Primary Tumors

- Primary tumors can be cancerous (malignant) or benign.
- These tumours start in the brian and do not spread.
- They rarely spread beyond the central nervous system.
- The tumor is still taking up space in the skull.
- They can cause serious complications and symptoms.

Benign Brain Tumors
- These are tumors that remain in the part of the brain in which they started.
- They don’t spread into and destroy other areas of the brain.
- They do not spread to other parts of the body.
- A benign tumour can be removed successfully.
- This shall cause no more problem once removed.
- Some benign tumours will regrow slowly.
- These tumours are treated with radiotherapy or further surgery may be needed.

Malignant Primary Brain Tumors
- These are most likely to cause problems by spreading into the normal brain tissue.
- This causes pressure and damage to the surrounding areas of the brain.
- These tumors rarely spread outside the brain to other parts of the body.

Secondary Tumors

- These tumors are often called metastatic tumors.
- They are the result of cancer cells originating from another part of the body.
- They are spread to the brain.
- Secondary brain tumors often indicate advanced stages of disease.
- Both cancerous primary and secondary tumors are life threatening.
- These types of tumors are usually very aggressive.
- Secondary tumors means a cancerous neoplasm that has developed in another organ elsewhere in the body.
- These cancer cells have leaked from that primary tumor and then entered the lymphatic system and blood vessels.
- They then circulate through the bloodstream.
- They are then deposited in the brain.
- These cells continue growing and dividing.
- They become another invasive neoplasm of the primary cancer’s tissue.
- Secondary tumors of the brain are very common in the terminal phases of patients.

The most common types of cancers that bring about secondary tumors of the brain are:
- lung cancer
- breast cancer
- malignant melanoma
- kidney cancer
- colon cancer
- cervical cancer

Signs and Symptoms of secondary tumors:
- In lymph nodes, a common symptom is lymphadenopathy.
- Lungs: cough, hemoptysis and dyspnea (shortness of breath).
- Liver: hepatomegaly (enlarged liver) and jaundice.
- Bones: bone pain, fracture of affected bones.
- Brain: neurological symptoms such as headaches, seizures, and vertigo.
Secondary tumor is occurred by four routes:
- Transcoelomic
- Lymphatic spread
- Haematogenous spread
- Transplantation or implantation

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