Posts Tagged ‘Factors’

How can we prevent and diagnose Osteoporosis

May 17th, 2010

To reach optimal peak bone mass and continue building new bone tissue as you age, you should consider several factors.
- Calcium: An inadequate supply of calcium over a lifetime contributes to the development of osteoporosis. Food sources of calcium include low-fat dairy products, such as milk, yogurt, cheese, and ice cream; dark green, leafy vegetables, such as broccoli, collard greens, bok choy, and spinach; sardines and salmon with bones; tofu; almonds; and foods fortified with calcium, such as orange juice, cereals, and breads.
- Vitamin D: Vitamin D plays an important role in calcium absorption and bone health. It is synthesized in the skin through exposure to sunlight. Food sources of vitamin D include egg yolks, saltwater fish, and liver.
- Smoking: Women who smoke have lower levels of estrogen compared with nonsmokers, and they often go through menopause earlier. Smokers also may absorb less calcium from their diets.
- Exercise: Like muscle, bone is living tissue that responds to exercise by becoming stronger. Weight-bearing exercise is the best for your bones because it forces you to work against gravity.
- Alcohol: Regular consumption of 2 to 3 ounces a day of alcohol may be damaging to the skeleton, even in young women and men.
- Medications that cause bone loss: The long-term use of glucocorticoids (medications prescribed for a wide range of diseases, including arthritis, asthma, Crohn’s disease, lupus, and other diseases of the lungs, kidneys, and liver) can lead to a loss of bone density and fracture.

Diagnosis of Osteoporosis

Women who have had a fracture due to fragility are diagnosed with severe osteoporosis and have a high risk for another fracture. Early diagnosis can prevent fractures and slow deterioration of bone tissue.
If the doctor suspects osteoporosis, a bone scan would be suggested. – A common test that measures bone density is called a dual energy X-ray absorptiometry (DEXA). This test measures the density of the bones in your hips, spine and wrist, which are all places likely to be affected by osteoporosis.
- Quantitative computed tomography (QCT) measures bone density in the hip and spine and produces a three-dimensional image that shows true volume density. QCT has the capacity to isolate an area for testing. The radiation level in QCT is 10 times higher than in DEXA.
- Peripheral bone density testing uses ultrasound to identify bone loss in a localized area such as the heel or hand.
Doctor may also order an ultrasound or a computerized tomography (CT) scan to help check the density of your bones.

What Is a Thyroid Cancer Prognosis?

April 28th, 2010

A thyroid cancer prognosis is a medical opinion as to the likely course and outcome of the disease. Factors that can affect a prognosis for a person with thyroid cancer include such things as the type and location of the cancer, the stage of the disease, its grade; and the patient’s age and general health.
People facing thyroid cancer are naturally concerned about what the future holds. Understanding thyroid cancer and what to expect can help patients and their loved ones:
- Plan thyroid cancer treatment.
- Think about lifestyle changes.
- Make decisions about their quality of life and finances.

A prognosis is a medical opinion as to the likely course and outcome of a disease. In other words, the prognosis is the chance that a patient will recover or have a recurrence (return of the cancer). There are many factors that can affect a person’s prognosis, which include:
- The type and location of the cancer.
- The stage of the disease (the extent to which the cancer has metastasized, or spread).
- Its grade (how abnormal the cancer cells look, and how quickly the cancer is likely to grow and spread).
- The person’s age, general health, and response to treatment.

Most thyroid cancers are very curable. In fact, the most common types of thyroid cancer, papillary and follicular, are the most curable. In younger patients, both papillary and follicular cancers have a more than 97% cure rate if treated appropriately. Both papillary and follicular cancers are typically treated with complete removal of the lobe of the thyroid that harbors the cancer, in addition to the removal of most or all of the other side.
The bottom line is that most thyroid cancers are papillary thyroid cancer, and this is one of the most curable cancers of all cancers that humans get. Treated correctly, the cure rate is extremely high.
Medullary cancer of the thyroid is significantly less common, but has a worse prognosis. Medullary cancers tend to spread to large numbers of lymph nodes very early on, and therefore require a much more aggressive operation than the more localized thyroid cancers, such as papillary and follicular. This cancer requires complete thyroid removal plus a dissection to remove the lymph nodes of the front and sides of the neck.
The least common type of thyroid cancer is anaplastic which has a very poor prognosis. Anaplastic thyroid cancer tends to be found after it has spread and is incurable in most cases.

How Are Bone Cancers Staged ?

March 22nd, 2010

Staging is a process that tells the doctor how wide spread a cancer may be. It will show whether the cancer has spread and how far. The treatment will depend on what stage has the bone cancer reached.
The American Joint Commission on Cancer has devised a system to stage bone cancer based on three factors.
- T stands for the size of the tumor.
- N stands for lymph node involvement.
- M stands for spread (metastasis) to distant organs.
- G stands for the tumor grade.

T stages of bone cancer :
TX: Primary tumor can’t be measured.
T0: No evidence of the tumor.
T1: Tumor is 8 cm (around 3 inches) or less.
T2: Tumor is larger than 8 cm.
T3: Tumor is in more than one place on the same bone.

N Stages :
N0: No spread to nearby (regional) lymph nodes.
N1: Cancer detected in nearby lymph nodes.

M Stages :
M0: No distant metastasis.
M1: Distant metastasis (cancer has spread to other tissues or organs).
M1a: Cancer has spread only to the lung.
M1b: Cancer has spread to other sites.

Grades :
G1–G2: Low grade
G3–G4: High grade

Once all of these stages have been determined in a particular case of cancer, the data are combined, and an overall stage is given to the disease.
- Stage IA: T1, N0, M0, G1-G2: Tumor is confined to the bone, less than 8 cm in size, and is low grade.
- Stage IB: T2, N0, M0, G1-G2: Tumor is confined to the bone, larger than 8 cm, and is low grade.
- Stage IIA: T1, N0, M0, G3-G4: Tumor is confined to the bone, less than 8 cm, and is high grade.
- Stage IIB: T2, N0, M0, G3-G4: Tumor is confined to the bone, larger than 8 cm, and is high grade.
- Stage III: T3, N0, M0, Any G: Tumor is confined to the bone but tumor cells are detected at other sites on the bone.
- Stage IVA: Any T, N0, M1a, Any G: Tumor has spread to the lung.
- Stage IVB: Any T, N1, Any M, Any G: Tumor has spread to lymph nodes and distant sites, or Any T, Any N, M1b, Any G: Tumor has spread to distant sites other than the lung.

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