How is liver cancer diagnosed?
Liver cancer is also known as hepatocellular carcinoma, HCC. It is a cancer that originates in liver. Liver cancers are malignant tumors that grow on the surface or inside the liver.
Diagnosis of Liver Cancer
Blood Tests
- Liver cancer depends so much on the vigilance of the physician screening with a tumor marker (alpha-fetoprotein) in the blood and radiological imaging studies.
- If the blood tests become abnormal or worsen due to liver cancer, this usually signifies extensive cancerous involvement of the liver.
- in liver cancer, the cancerous liver cells may take on the characteristics of other types of cells.
- For example, liver cancer cells sometimes can produce hormones that are ordinarily produced in other body systems.
- These hormones then can cause certain abnormal blood tests
- These include a high red blood count (erythrocytosis), low blood sugar (hypoglycemia) and high blood calcium (hypercalcemia).
- High serum cholesterol (hypercholesterolemia), is seen in up to 10% of patients from Africa with liver cancer.
- The high cholesterol occurs because the liver cancer cells are not able to turn off (inhibit) their production of cholesterol.
- There is no reliable or accurate screening blood test for liver cancer.
- The most widely used biochemical blood test is alpha-fetoprotein (AFP)
- AFP is a protein normally made by the immature liver cells in the fetus.
In adults, high blood levels (over 500 nanograms/milliliter) of AFP are seen in only three situations:
- Liver cancer.
- Germ cell tumors (cancer of the testes and ovaries).
- Metastatic cancer in the liver (originating in other organs).
There are a number of other liver cancer tumor markers like:
- Des-gamma-carboxyprothrombin (DCP),
- A variant of the gamma-glutamyltransferase enzymes,
- Variants of other enzymes (for example, alpha-L-fucosidase).
Imaging Studies
These studies provide information
- as to the size of the tumor.
- the number of tumors.
- whether the tumor has involved major blood vessels locally or spread outside of the liver.
Ultrasound Examination
- It is usually the first study ordered if liver cancer is suspected in a patient.
- The accuracy of an ultrasound depends very much on the technician and radiologist.
- Computerized axial tomography (CT scan) is a very common study used in the U.S.
- The ideal CT study is a multi-phase, spiral CT scan using oral and intravenous contrast material.
Pictures are taken in three phases:
- Without intravenous contrast.
- With intravenous contrast (enhanced imaging) that highlights the arterial system (arterial phase).
- When the contrast is in the venous phase.
Magnetic Resonance Imaging (MRI)
- It can provide very clear images of the body.
- Its advantage over CT is that MRI can provide sectional views of the body in different planes.
Others
- If there is uncertainty about the diagnosis, the presence of liver cancer may be confirmed with a biopsy.
- Tissue from the liver is removed through a needle or during an operation and checked under a microscope for the presence of cancer cells.
- Laproscopy is another method.
Staging
The following stages are used for adult primary liver cancer:
- Localized resectable
Cancer is found in one place in the liver and can be completely removed by surgery.
- Localized unresectable
Cancer is found only in one part of the liver, but the cancer cannot be totally removed.
- Advanced
Cancer has spread through much of the liver or to other parts of the body.
- Recurrent
Cancer has come back or recurred after it was treated. It may come back in the liver or in another part of the body.
Categories: Body, Cancer, Cells, Complications, cure, Detection, Diagnosis, digestion, Digestive System, Disease, Disorder, growth, health, Healthy, Liver, Metabolism Tags: Blood tests, Body, Brain, Break down, Chemicals, Cholesterol, Detoxification, Detoxify, Diagnosis, digestion, Fats, Functions, health, Healthy, Human, Imaging, Liver, Metabolism, MRI, Organs, Regulate, Staging, Store, Sugar, Ultrasound, Vital
Adrenal Gland Cancer – Tests
Adrenal Gland cancer is a very rare type of cancer that is caused due to the excessive production of hormones in the adrenal gland. The condition can get fatal if not diagnosed in time and therefore one must pay attention to the symptoms and consult and expert if they think they could be suffering from adrenal cancer.
There are a number of ways to diagnose the condition and your expert will carry out necessary tests to check whether you are suffering from the disease. Below mentioned are a few diagnostic measures that doctors may adhere to while checking you for adrenal cancer.
Blood tests: Most doctors will ask you to get blood tests done to check the circulation of hormones in the body. Excessive production of certain hormones like cortisol, estrogen, aldosterone, testosterone are characteristic to the cancer and therefore blood tests serve as a good starting point.
However both malignant and benign tumors cause the over production of hormones and are not indicators of whether the tumor is malignant or benign. Therefore the tests are non conclusive and would need to be complimented with other tests to check the tumors
There are four X-Ray tests that are primarily used for the detection of a tumor in the adrenal gland:
Ultrasound: The ultrasound is most commonly used to examine one’s adrenal gland and kidneys. The ultrasound test however may not be as accurate as the CT Scan and therefore is not preferred as the best method to detect tumors. The test however can be used to detect any kind of adrenal tumor.
CT Scan: The CT Scan also known as the CAT Scan is another common way of examining whether a patient is suffering from adrenal cancer. It can be used to detect any type of adrenal tumor and is painless. The procedure is not long and only takes about 30 minutes. It is one of the most accurate ways of examining the adrenal glands for tumors. The pictures generated help in sizing up the tumors well that help in planning the treatments that should be taken up.
The scan identifies the following:
Left adrenal gland
Left Kidney
Pancreas
Spleen outline
MRI Scan: The MRI Scan is similar to the CAT Scan. It is also known as the MR Scan or the NMR Scan. The MRI scan takes about an hour to complete and deploys magnetic fields to produce pictures unlike x-ray like images that the CAT scan generates or sound waves that you get from an ultra sound.
Pheochromocytomas light up on an MRI Scan making it one of the most accurate ways of detecting adrenal tumors of any type.
MIBG Scan: The MIBG scan is used to detect the location and presence of adrenal pheochromocytomas. The test is ineffective in detecting other types of adrenal tumors.
Most doctors will utilize the above mentioned tests to examine your body for adrenal tumors. However it is essential that you seek the guidance of an expert when it comes to adrenal gland cancer as you need to ensure that the proper treatment is adhered to after the tumor is detected be it malignant or benign.
When you consult a doctor who is recognized you can be sure that you will receive the best treatment. Over and above medication and surgeries you need to pay attention to your diet and make efforts to stay healthy by indulging in physical exercise. The medication can lead you to feeling tired and lethargic and therefore you should try and fight the illness itself with your mind and try and keep a brave front. If you are willing to fight the disease it can be defeated.
Categories: Cancer, Test Tags: Adrenal Cancer, Blood Test, Cancer, CAT Scan, Malignant, MIBG Scan, Mitotane, MRI, Surgery, Symptoms, Tests, Treatment, Tumor, Ultrasound
How is Leukemia diagnosed ?
Leukemia can be diagnosed with a variety of tests, and understanding what each test is and what it looks for can make the tests a little less confusing. Doctors sometimes find leukemia after a routine blood test. If you have symptoms that suggest leukemia, your doctor will try to find out what’s causing the problems. Your doctor may ask about your personal and family medical history.
- Physical Examination
An exam is much like any doctor’s appointment; the doctor will take a detailed medical history and thoroughly examine the whole body.
- Blood Tests
To diagnose leukemia, a number of blood tests are performed. These tests are used to evaluate the type and quantity of blood cells that are present, the blood chemistry, and other factors.
- Full blood count
It is used to establish the numbers of different blood cell types in the circulation. A low number of red or white blood cells is described as anemia or leukopenia, respectively.
- Bone Marrow Biopsy
A biopsy takes a small sample of bone marrow tissue from the body. The doctor asks the patient to lie on his or her side and nurses clean the biopsy site with iodine or alcohol. After the site is cleaned, the biopsy site is numbed with a local anesthetic. The doctor uses either a very fine needle to draw out only bone marrow tissue, or a thicker needle to take a small sample of bone and bone marrow. The bone marrow sample is examined under a microscope to check for leukemia cells.
- Cytogenetics
It is a newer type of testing for leukemia. Cytogenetic testing uses a sample taken from a blood draw or a bone marrow or lymph node biopsy. The sample’s chromosomes are microscopically examined for abnormalities that indicate damage to the cells’ DNA.
- Spinal tap
The doctor uses a long, thin needle to remove fluid from the lower spine. The procedure takes about 30 minutes and is performed with local anesthesia. You must lie flat for several hours afterward to keep from getting a headache.
- Chest x-ray
An x-ray can show swollen lymph nodes or other signs of disease in your chest.
- CT scan of the head, chest, and belly, to find out whether leukemia has spread there.
- Lumbar puncture is to find out whether leukemia cells are in your cerebrospinal fluid (CSF).
- Differential blood count (DBC)
It is used to determine the relative proportion of blood cell types within the bloodstream. In particular, the percentage of immature leukemic “blast” cells is noted.
- Hematocrit assay
It is used to determine the proportion of the blood that is occupied by erythrocytes (red blood cells). In adult men, normal is about 46% (39.8–52.2) and in adult women, it is about 40.9% (34.9–46.9).
Categories: Acute lymphocytic leukemia, Acute Myelogenous Leukemia, Cancer, causes, cure, Diagnosis, growth, health, Leukemia Tags: Biopsy, Blood, Blood cells, Blood tests, Body, Cancer, causes, Cells, CT Scan, Diagnosis, health, immature, immune system, Leukemia, Methods, MRI, Organs, Tissues, X-ray

Click here.