Posts Tagged ‘Symptoms’

What are the different methods available for the treatment of osteoporosis?

May 18th, 2010

Osteoporosis (or porous bone) is a disease in which bones become weak and, therefore, are more likely to break. Without prevention or treatment, osteoporosis can progress without pain or symptoms until a bone breaks (fractures).

Hormone replacement therapy (HRT)

Oestrogen seems to protect bone strength. The drop in oestrogen that occurs following menopause is mirrored by an increased loss of bone for a few years thereafter. The loss continues, but less steeply, in older women. Hormone replacement therapy replaces oestrogen and so reduces the rate of bone loss. HRT is thought to be of most benefit for preventing osteoporosis if it is started early in menopause and is taken for at least five years. Briefly, HRT is known to be associated with an increased risk of breast cancer, cancer of the lining of the womb (endometrial cancer), blood clots in the veins (thrombosis), stroke and heart disease.
HRT remains an option for women over 50 at risk of fractures for whom these other medicines are not suitable. HRT is also still a suitable option for women who have had an early menopause.

Bisphosphonates

Bisphosphonates are medications that slow the breakdown and removal of bone (ie, resorption). They are widely used for the prevention and treatment of osteoporosis in postmenopausal women. The most common side effects associated with bisphosphonates are digestive in nature, for example indigestion, diarrhoea, constipation and abdominal pain.

Kyphoplasty

It is also known as balloon kyphoplasty is a newer procedure. It involves placing a catheter with a balloon into a compressed vertebral body and slowly inflating the balloon to reduce the fracture. A special surgical cement is then injected into the space created by the balloon. The procedure stabilizes the fracture and restores vertebral body height.

Vertebroplasty

It is similar to Kyphoplasty, except a balloon is not used in this procedure.

Strontium ranelate

Strontium ranelate (Protelos) is used for the treatment of osteoporosis in postmenopausal women. It is usually reserved for women who cannot take bisphosphonates.

Raloxifene

Raloxifene (Evista) is a type of medicine called a selective oestrogen receptor modulator (SERM). It can be used to both prevent and treat osteoporosis in postmenopausal women.

How can we prevent and diagnose Osteoporosis

May 17th, 2010

To reach optimal peak bone mass and continue building new bone tissue as you age, you should consider several factors.
- Calcium: An inadequate supply of calcium over a lifetime contributes to the development of osteoporosis. Food sources of calcium include low-fat dairy products, such as milk, yogurt, cheese, and ice cream; dark green, leafy vegetables, such as broccoli, collard greens, bok choy, and spinach; sardines and salmon with bones; tofu; almonds; and foods fortified with calcium, such as orange juice, cereals, and breads.
- Vitamin D: Vitamin D plays an important role in calcium absorption and bone health. It is synthesized in the skin through exposure to sunlight. Food sources of vitamin D include egg yolks, saltwater fish, and liver.
- Smoking: Women who smoke have lower levels of estrogen compared with nonsmokers, and they often go through menopause earlier. Smokers also may absorb less calcium from their diets.
- Exercise: Like muscle, bone is living tissue that responds to exercise by becoming stronger. Weight-bearing exercise is the best for your bones because it forces you to work against gravity.
- Alcohol: Regular consumption of 2 to 3 ounces a day of alcohol may be damaging to the skeleton, even in young women and men.
- Medications that cause bone loss: The long-term use of glucocorticoids (medications prescribed for a wide range of diseases, including arthritis, asthma, Crohn’s disease, lupus, and other diseases of the lungs, kidneys, and liver) can lead to a loss of bone density and fracture.

Diagnosis of Osteoporosis

Women who have had a fracture due to fragility are diagnosed with severe osteoporosis and have a high risk for another fracture. Early diagnosis can prevent fractures and slow deterioration of bone tissue.
If the doctor suspects osteoporosis, a bone scan would be suggested. – A common test that measures bone density is called a dual energy X-ray absorptiometry (DEXA). This test measures the density of the bones in your hips, spine and wrist, which are all places likely to be affected by osteoporosis.
- Quantitative computed tomography (QCT) measures bone density in the hip and spine and produces a three-dimensional image that shows true volume density. QCT has the capacity to isolate an area for testing. The radiation level in QCT is 10 times higher than in DEXA.
- Peripheral bone density testing uses ultrasound to identify bone loss in a localized area such as the heel or hand.
Doctor may also order an ultrasound or a computerized tomography (CT) scan to help check the density of your bones.

What is osteoporosis and what are the signs and symptoms of osteoporosis ?

May 16th, 2010

Osteoporosis is a disease characterized by low bone mass and loss of bone tissue that may lead to weak and fragile bones. Osteoporosis is a disease of bones that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone micro architecture is disrupted, and the amount and variety of proteins in bone is altered.
Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men.

Causes of Osteoporosis

- Osteoporosis occurs when there is an imbalance between new bone formation and old bone resorption.
- The body may fail to form enough new bone, or too much old bone may be reabsorbed, or both.
- The leading cause of osteoporosis is a lack of certain hormones, particularly estrogen in women and androgen in men.
- Other factors that may contribute to bone loss in this age group include inadequate intake of calcium and vitamin D, lack of weight-bearing exercise, and other age-related changes in endocrine functions.

Symptoms of Osteoporosis

Osteoporosis can be present without any symptoms for decades because osteoporosis doesn’t cause symptoms until bone fractures. he symptom associated with osteoporotic fractures usually is pain; the location of the pain depends on the location of the fracture.

Risk factors of Osteoporosis

- Getting older.
- Being small and thin.
- Having a family history of osteoporosis.
- Taking certain medicines.
- Being a white or Asian woman.
- Having osteopenia, which is low bone mass.
- Cigarette smoking, eating disorders such as anorexia nervosa or bulimia, low amounts of calcium in the diet, heavy alcohol consumption, inactive lifestyle, and use of certain medications, such as corticosteroids and anticonvulsants, are also risk factors.
- Rheumatoid arthritis itself is a risk factor for osteoporosis.

Facts and Figures

- Osteoporosis is a major public health threat for 44 million Americans, 68 percent of whom are women.
- One out of every two women and one in four men age 50 and older will have an osteoporosis-related fracture in their lifetime.
- Osteoporosis can strike at any age.
- Osteoporosis is responsible for more than 1.5 million fractures annually, including approximately 300,000 hip fractures, 700,000 vertebral fractures, 250,000 wrist fractures, and more than 300,000 fractures at other sites.

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